Transverse myelitis (TM) is an acute inflammation of spinal cord characterized by demyelination. Infectious, inflammatory and autoimmune etiologies constitute the most common etiologies of TM. It is believed that pathlogical changes in infection related cases occur due to altered immune response rather than direct effect of the infection. Methicillin resistant Staphylococcus aureus (MRSA) a well known agent of hospital and sometimes community acquired pneumonia leads to increased morbidity and mortality. Here we describe a case of transverse myelitis as an unusual complication of MRSA pneumonia. To our knowledge, this is the first reported case of transverse myelitis developed with MRSA pneumonia.