Angiotropic lymphoma: A Concealed Etiology of Fever of Unknown Origin
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Pennsylvania Hospital, Philadelphia, USA
Publication date: 2010-04-12
Corresponding author
Tabassum Nafsi   

Department of Medicine, Pennsylvania Hospital, 800 Spruce Street, 1 Pine West, Philadelphia, PA 19107
Eur J Gen Med 2010;7(2):234-239
A 67 year old female presented with generalized weakness, falls and recurrent high grade fevers for 5 - 6 weeks. Physical findings included high grade temperature, lower extremity weakness and diminished reflexes. An extensive work-up for fever of unknown origin (FUO), including PET-FDG scan, did not yield any occult infectious or neoplastic process. Ultimately a temporal artery biopsy was planned to rule out temporal arteritis. The histopathology of temporal artery was normal while the vein showed lymphoid proliferation consistent with Angiotropic large cell lymphoma (ALCL).
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