Juvenile Granulosa Cell Tumor and High Blood Ca-125 Levels in Children with Pseudo-Meigs Syndrome
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Department of Pediatric Surgery, Selcuk University, Medical Faculty, Konya, Turkey
Department of Pediatric Endocrinology, Suleyman Demirel University, Medical Faculty, Isparta, Turkey
Department of Pathology, Konya Training and Research Hospital, Konya, Turkey
Publication date: 2013-10-09
Corresponding author
İlhan Ciftci   

M.D., Selcuk Universitesi Tip Fakultesi, Cocuk Cerrahisi A. D. Konya, Turkey
Eur J Gen Med 2013;10(4):239-242
Ovarian tumors and cysts are rarely seen in children. They constitute 1-2% of solid tumors among children. Over tumors are categorized into three main groups: epithelial, embrionic, and sex cord-stromal tumors. Sex cord-stromal tumors arise from primordial cell cords that are located in the center of the ovary during embriological development. We have detected a patient who was diagnosed with a juvenile granulosa cell tumor (JGCT) at two years of age after presenting with excessive breast enlargement during the past month. She had a large mass in the abdomen, ascites, and marked pleural effusion in the right hemithorax. This association was Pseudo-Meigs syndrome. The association of JGCT and Pseudo-Meigs syndrome is a considerably rare event. Moreover, since the patient was the youngest among all previously reported cases in existing literature, our observations indicate that a juvenile granulosa cell tumor may occur at an early age.In conclusion, Pseudo-Meigs syndrome with JGCT shouldn't forget, even in young children.
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