ORIGINAL ARTICLE
Abdominal Diameter Profiles have Relationship with Insulin Resistance in Obese Female Adolescents
 
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1
Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Central Java, INDONESIA
 
2
Center of Nutrition Resaerch, Faculty of Medicine, Universitas Diponegoro, Semarang, Central Java, INDONESIA
 
 
Online publication date: 2020-04-05
 
 
Publication date: 2020-04-05
 
 
Electron J Gen Med 2020;17(5):em219
 
KEYWORDS
ABSTRACT
Purpose:
This study aimed to determine the relationship of abdominal diameter consist of Sagital Abdominal Diameter (SAD), Ratio SAD/Height and Abdominal Diameter Index (ADI) with insulin resistance in obese female adolescents.

Method:
This study was conducted in June-August 2019 at Universitas Diponegoro, Central Java. this study used cross sectional design with a total of 120 female students aged 17-21 years and selected using purposive sampling method. Study variables included SAD, SAD/Height, ADI and insulin resistance level. SAD was measured by abdominal caliper, SAD/Height was ratio of SAD divided by height. ADI was ratio of SAD divided by thigh circumference. The value of insulin resistance was obtained from the calculation of homeostasis model assessment insulin resistance (HOMA-IR). Data normality was analyzed by Kolmogorov-smirnov test, all data were not normal distribution so the bivariate test analyzed by Rank spearman test.

Results:
As many as 42.5% subjects had SAD which included at risk and 83.3% subjects had suffering insulin resistance. There was significant relationship between SAD, SAD/Height, ADI with insulin resistance (SAD (p=0.001), SAD/Height (p<0.001) and ADI (p=0.003). In addition, SAD, SAD/Height, ADI were significant relationship with fasting blood glucose (SAD (p=0.048), SAD/Height (p=0.022) and ADI (p=0.003).

Conclusion:
There were significant relationship between SAD, SAD/Height, ADI with insulin resistance and fasting blood glucose in obese adolescent female.

 
REFERENCES (33)
1.
Ramachandran A, Snehalatha C. Rising burden of obesity in Asia. Journal of Obesity, 2010:1-7. https://doi.org/10.1155/2010/8... PMid:20871654 PMCid:PMC2939400.
 
2.
Ministry of Health Republic of Indonesia. Riset Kesehatan 2013. Jakarta: Health Research and Development Agency Ministry of Health Republic of Indonesia. 2013.
 
3.
Ministry of Health Republic of Indonesia. Riset Kesehatan Dasar 2018. Jakarta: Health Research and Development AgencyMinistry of Health Republic of Indonesia. 2018.
 
4.
Hanifah NID, Dieny FF. Hubungan Total Asupan Serat, Serat Larut Air (Soluble), Dan Serat Tidak Larut Air (Insoluble) Dengan Kejadian Sindrom Metabolik Pada Remaja Obesitas. Journal of Nutrition College, 2016;5(3):148-55. https://doi.org/10.14710/jnc.v....
 
5.
Sudikno S, Syarief H, Dwiriani CM, Riyadi H. Faktor Risiko Obesitas Sentral Pada Orang Dewasa Umur 25-65 Tahun Di Indonesia (Analisis Data Riset Kesehatan Dasar 2013). The Journal of Nutrition and Food Research, 2016;38(2). https://doi.org/10.22435/pgm.v....
 
6.
Ye J. Mechanisms of Insulin Resistance in Obesity. Frontiers of Medicine in China, 2013;7(1):14-24. https://doi.org/10.1007/s11684... PMid:23471659 PMCid:PMC3936017.
 
7.
Westphal SA. Obesity, Abdominal Obesity, and Insulin Resistance. Clinical Cornerstone, 2008;9(1):23-31. https://doi.org/10.1016/S1098-....
 
8.
dos Santos Romualdo MC, de Nobrega FJ, Escrivao MAMS. Insulin Resistance in Obese Children and Adolescents. Jornal de Pediatria, 2014;90(6):600-7. https://doi.org/10.1016/j.jped... PMid:25019650.
 
9.
Nuraini IS, Sulchan M, Dieny FF. Resistensi Insulin pada Remaja Stunted Obesity Usia 15-18 Tahun di Kota Semarang. Journal of Nutrition College, 2017;6(2):164-71. https://doi.org/10.14710/jnc.v....
 
10.
Carneiro Roriz AK, Santana Passos LC, Cunha De Oliveira C, Eickemberg M, De Almeida Moreira P, Barbosa Ramos L. Anthropometric Clinical Indicators in the Assessment of Visceral Obesity: an Update. Nutricion Clinica Dietetica Hospitalaria, 2016;36(2):168-79. https://doi.org/10.12873/362ca....
 
11.
Anjana M, Sandeep S, Deepa R, Vimaleswaran KS, Farooq S, Mohan V. Visceral and Central Abdominal Fat and Anthropometry in Relation to Diabetes in Asian Indians. Diabetes Care, 2004;27(12):2948-53. https://doi.org/10.2337/diacar... PMid:15562212.
 
12.
Firouzi SA, Tucker LA, LeCheminant JD, Bailey BW. Sagittal abdominal diameter, waist circumference, and BMI as predictors of multiple measures of glucose metabolism: An NHANES investigation of US adults. Journal of Diabetes Research, 2018:1-14. https://doi.org/10.1155/2018/3... PMid:30018985 PMCid:PMC6029495.
 
13.
Gletsu-Miller N, Kahn HS, Gasevic D, Liang Z, Frediani JK, Torres WE, et al. Sagittal abdominal diameter and visceral adiposity: Correlates of beta-cell function and dysglycemia in severely obese women. Obesity Surgery, 2013;23(7):874-81. https://doi.org/10.1007/s11695... PMid:23408092 PMCid:PMC3750719.
 
14.
Khan HS, Rissanen H, Bullard KM, Knekt P. The Population Distribution of the Sagittal Abdominal Diameter (SAD) and SAD/height Ratio Among Finnish Adults. Clinical Obesity, 2014;4(6):333-41. https://doi.org/10.1016/j.phys... PMid:28363838 PMCid:PMC5510739.
 
15.
Ehrlich AC, Smith DA. Abdominal Diameter Index and 12-year Cardiovascular Disease Incidence in Male Bridge and Tunnel Workers. International Journal of Obesity, 2011;35(3):409-15. https://doi.org/10.1038/ijo.20... PMid:20714330.
 
16.
Roriz AKC, Passos L, Oliveira C, Eickemberg M, Moreira P, Ramos L. Discriminatory Power of Indicators Predictors of Visceral Adiposity Evaluated by Computed Tomography in Adults and Elderly Individual. Nutricion Hospitalaria, 2014;29(6):1401-7. https://doi.org/10.3305/nh.201....
 
17.
Sampaio LR, Simões EJ, Assis AMO, Ramos LR. Validity and reliability of the sagittal abdominal diameter as a predictor of visceral abdominal fat. Arquivos Brasileiros de Endocrinologia e Metabologia, 2007;51(6):980-6. https://doi.org/10.1590/s0004-... PMid:17934666.
 
18.
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetalogia, 1985;28:412-9. https://doi.org/10.1007/BF0028... PMid:3899825.
 
19.
Pereira PF, Serrano HMS, Carvalho GQ, Ribeiro SMR, et al. Measurements of body fat distribution: assessment of collinearity with body mass, adiposity and height in female adolescents. Revista Paulista de Pediatria, 2015;33(1):63-71. https://doi.org/10.1016/S2359-....
 
20.
Stokic E, Srdic B, Brtka V, Tomic-Nagalic D. Sagittal Abdominal Diameter as the Anthropometric Measure of Cardiovascular Risk, 2012:319-340. https://doi.org/10.5772/31677.
 
21.
Vasques ACJ, Cassani RSL, Forti ACe, Viiela BS, Pareja JC, Tambascia MA, et al. Sagittal Abdominal Diameter as a Surrogate Marker of Insulin Resistance in an Admixtured Population — Brazilian Metabolic Syndrome Study (BRAMS). PLOS ONE, 2015;2:1-13. https://doi.org/10.1371/journa... PMid:25951458 PMCid:PMC4423830.
 
22.
Riserus U, Faire Ude, Berglund L, Hellenius M-L. Sagittal Abdominal Diameter as a Screening Tool in Clinical Research: Cutoffs for Cardiometabolic Risk. Journal of Obesity, 2010:1-7. https://doi.org/10.1155/2010/7... PMid:20798888 PMCid:PMC2925288.
 
23.
Al-attas OS, Al-daghri NM, Alokail MS, Alkharfy KM, Draz H, Yakout S, et al. Association of body mass index, sagittal abdominal diameter and waist-hip ratio with cardiometabolic risk factors and adipocytokines in Arab children and adolescents. BMC Pediatrics, 2012;12(119):1-6. https://doi.org/10.1186/1471-2... PMid:22871266 PMCid:PMC3470957.
 
24.
González-Zavala MA, Velasco-Morales A, Terrazas-Flores JJ, de la Cruz-Galiciaae MG. Levels of insulin and HOMA-IR in adolescents in Saltillo, Coahuila, Mexico. Medicina Universtaria, 2015;17(67):80-7. https://doi.org/10.1016/j.rmu.....
 
25.
Yi KH, Hwang JS, Kim EY, Lee SH, Kim DH, Lim SJ. Prevalence of insulin resistance and cardiometabolic risk in Korean children and adolescents: A population-based study. Diabetes Research and Clinical Practice, 2014;103(1):106-13. https://doi.org/10.1016/j.diab... PMid:24290751.
 
26.
Ramadhan NR, Wijayanti HS. Dietary Acid Load, Keseimbangan Asam Basa Tubuh dan Resistensi Insulin pada Remaja Obesitas. Journal of Nutrition College, 2017;6(1):69-75. https://doi.org/10.14710/jnc.v....
 
27.
Singh Y, Garg MK, Tandon N, Marwaha RK. A Study of Insulin Resistance by HOMA-IR and its Cut-off Value to Identify Metabolic Syndrome in Urban Indian Adolescents Yashpal. Journal of Clinical Research in Pediatric Endocrinology, 2013;5(4):245-51. https://doi.org/10.4274/Jcrpe.... PMid:24379034 PMCid:PMC3890224.
 
28.
Krishnappa SK, Yashoda HT, Boraiah G, Vishwa S. Sagittal Abdominal Diameter to Measure Visceral Adipose Tissue in Overweight or Obese Adolescent Children and Its Role as A Marker of Insulin Resistance. Journall of Clinical and Diagnostic Research, 2015;9(11):9-12. https://doi.org/10.7860/JCDR/2... PMid:26673888 PMCid:PMC4668495.
 
29.
Moon HU, Ha KH, Han SJ, Kim HJ, Kim DJ. The Association of Adiponectin and Visceral Fat with Insulin Resistance and β -Cell Dysfunction. Journal of Korean Medical Science, 2019;34(1):1-12. https://doi.org/10.3346/jkms.2... PMid:30618514 PMCid:PMC6318440.
 
30.
Donohoe CL, Doyle SL, Reynolds JV. Visceral Adiposity, Insulin Resistance and Cancer Risk. Diebetoogy & Metabolic Syndrome, 2011;12(3):1-13. https://doi.org/10.1186/1758-5... PMid:21696633 PMCid:PMC3145556.
 
31.
Castro AVB, Koika CM, Kim SP, Bergman RN. Obesity, Insulin Resistence and Cormobidities - Mechanisms of Association. Arq Bras Endocrinol Metabol, 2015;58(6):600-9. https://doi.org/10.1159/000398....
 
32.
Kantartzis K, MacHann J, Schick F, Fritsche A, Häring HU, Stefan N. The Impact of Liver Fat VS Visceral Fat in Determining Categories of Prediabetes. Diabetologia, 2010;53(5):882-9. https://doi.org/10.1007/s00125... PMid:20099057.
 
33.
Borel AL, Nazare JA, Smith J, Aschner P, Barter P, Van Gaal L, et al. Visceral, subcutaneous abdominal adiposity and liver fat content distribution in normal glucose tolerance, impaired fasting glucose and/or impaired glucose tolerance. International Journal of Obesity, 2015;39(3):495-501. https://doi.org/10.1038/ijo.20... PMid:25179244.
 
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