Collision tumor of the thyroid gland: Follicular carcinoma and papillary microcarcinoma
More details
Hide details
Department of Pathology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAUDI ARABIA
Department of Medicine, King Fahd Hospital of the University, Dammam, SAUDI ARABIA
Department of Surgery, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAUDI ARABIA
Publication date: 2022-08-29
Electron J Gen Med 2022;19(6):em411
Collision tumor represents the proximal coexistence of two histologically distinct tumors. The combination of two different types of tumors in a single thyroid gland is extremely unusual. We reported a case of follicular carcinoma and papillary microcarcinoma occur independently as a primary tumor separated by a normal tissue in a 59- year- old Saudi female, presented at the clinic with goiter for two months duration without symptoms of thyroid hormonal disorders. This case is one of few cases to be reported as a combined follicular thyroid carcinoma and papillary thyroid carcinoma in English literature.
Plauche V, Dewenter T, Walvekar RR. Follicular and papillary carcinoma: A thyroid collision tumor. Indian J Otolaryngol Head Neck Surg. 2013;65(Suppl 1):S182-4. PMid:24427641 PMCid:PMC3718925.
Lloyd RV, Osamura RY, Klöppel G, Rosai J. WHO classification of tumours. IARC;2017.
Takano K, Kikuchi K, Matsumiya H, Himi T. Collision tumor of the thyroid: Follicular carcinoma plus papillary carcinoma plus adenomatous goiter. World J Med Surg Case Rep. 2013;10:2320-2.
Baloch ZW, Mandel S, LiVolsi VA. Combined tall cell carcinoma and hurthle cell carcinoma (collision tumor) of the thyroid. Arch Pathol Lab Med. 2001;125:541-3. PMid:11260633.
Mohammadzadeh M, Pourzand A, Eftekhar-Sadat A-T, Alikhah H, Naghavi-Behzad M. A case of concurrent several forms of thyroid cancer. Niger Med J. 2013;54(5):351-3. PMid:24403717 PMCid:PMC3883239.
Thomas VP, George R. Collision tumors of the thyroid: Review of literature and report of a case of papillary–Follicular collision tumor. Thyroid Res Pract. 2018;15:60-4.
Rossi S, Fugazzola L, De Pasquale L. Medullary and papillary carcinoma of the thyroid gland occurring as a collision tumour: Report of three cases with molecular analysis and review of the literature. Endocr Relat Cancer. 2005;12:281-9. PMid:15947103.
Rekhi B, Badhe RR, Desouza MA, et al. A unique RET EXON 11 (G691S) polymorphism in an Indian patient with a collision tumor of the thyroid. Diagn Pathol. 2007;2:39. PMid:17939859 PMCid:PMC2164940.
Ryan N, Walkden G, Lazic D, Tierney P. Collision tumors of the thyroid: A case report and review of the literature. Head Neck. 2015;37(10):E125-9. PMid:25491252.
Brandwein-Gensler M, Urken M, Wang B. Collision tumor of the thyroid: A case report of metastatic liposarcoma plus papillary thyroid carcinoma. Head Neck. 2004;26:637-41. PMid:15229907.
Fortson JK, Durden FL Jr, Patel V, Darkeh A. The coexistence of anaplastic and papillary carcinomas of the thyroid: A case presentation and literature review. Am Surg. 2004;70:1116-9.
Jacobson AS, Wenig BM, Urken ML. Collision tumor of the thyroid and larynx: A patient with papillary thyroid carcinoma colliding with laryngeal squamous cell carcinoma. Thyroid. 2008;18:1325-8. PMid:19067640.
Walvekar RR, Kane SV, D’Cruz AK. Collision tumor of the thyroid: Follicular variant of papillary carcinoma and squamous carcinoma. World J SurgOncol. 2006;4:65. PMid:16984659 PMCid:PMC1622750.
Warman M, Lipschitz N, Ikher S, Halperin D. Collision tumor of the thyroid gland: Primary squamous cell and papillary thyroid carcinoma. ISRN Otolaryngology. 2011;2011: 582374. PMid: 23724255 PMCid:PMC3658539.
Abdelaal A, El Ansari W, Abusabeiba A, et al. Simultaneous occurrence of follicular and papillary thyroid carcinomas in same thyroid lobe: A case series of six patients from Qatar. Int J Surg Case Rep. 2020;73(2020):65-70. PMid:32645594 PMCid:PMC7341056.
Journals System - logo
Scroll to top