Infective Endocarditis caused by Streptococcus bovis may usually be associated with gastrointestinal pathologies, particularly colon cancer. S. bovis endocarditis may cause higher rates of neurological complications and more extensive valvular destruction compared to other microorganisms. This case report describes a patient with a recent history of rectal adenocarcinoma diagnosed as S. bovis endocarditis and complicated by intracranial and subarachnoidal hemorrhage after cardiac valve replacement. Because of high rates of neurological complications, these patients should be carefully followed up even after the medical and/or surgical treatment.