Impact of COVID-19 on mental health in the Middle East: A cross-sectional study
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Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, JORDAN
Researcher in Pharmacology and Medical Science, Department of Pharmacology, Faculty of Pharmacy, Mersin University, TÜRKİYE
MEU Research Unit, Middle East University, Amman, JORDAN
Department of Pharmaceutics & Pharmaceutical Technology, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, JORDAN
Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmacy, Applied Science Private University, Amman, JORDAN
Online publication date: 2023-08-01
Publication date: 2023-11-01
Electron J Gen Med 2023;20(6):em529
This study aimed to shed the light on the relation between the COVID-19 outbreak and mental health, including depression and anxiety in the Middle East.

This is a survey-based study that was conducted online to evaluate the impact of the COVID-19 pandemic on mental health in the Middle East countries. The survey was uploaded on Google Form platform and was distributed through Facebook and WhatsApp platform.

In this study, 1,281 respondents completed the online survey. Results showed higher percentages of anxiety were diagnosed post-pandemic (38.0%) compared to pre-pandemic (6.8%). Similarly, higher percentages of participants were diagnosed with depression post-pandemic (32.0%) compared with pre-pandemic (5.0%). Also, 43.4% of the participants showed that they always or most of the time felt ‘loss of desire or interest in things. Moreover, many participants (22.4%) always/most of the time felt cramps in their chest and heart as soon as they thought of the pandemic. Finally, logistic regression analysis emphasized that gender and age significantly affected the diagnosis of anxiety and depression following the pandemic (p≤0.005).

This current study highlighted an increase in the diagnosis of anxiety and depression among Middle Eastern following the COVID-19 pandemic. These findings revealed the importance of utilizing health coping or resilience strategies, mental health awareness campaigns, and education programs by the policymakers and stakeholders.

Harapan H, Itoh N, Yufika A, et al. Coronavirus disease 2019 (COVID-19): A literature review. J Infect Public Health. 2020; 13(5):667-73. https://doi.org/10.1016/j.jiph... PMid:32340833 PMCid:PMC7142680.
Wu D, Wu T. Liu Q, Yang Z. The SARS-CoV-2 outbreak: What we know. Int J Infect Dis. 2020;94:44-8. https://doi.org/10.1016/j.ijid... PMid:32171952 PMCid:PMC7102543.
WHO. World Health Organization coronavirus disease (COVID-19) dashboard. World Health Organization; 2020. Available at: https://covid19.who.int/ (Accessed: 15 April 2023).
Shahreen MA, Khan S, Kazmi A, Bashir N, Siddique R. COVID-19 infection: Origin, transmission, and characteristic of human coronaviruses. J Adv Res. 2020;24:91-8. https://doi.org/10.1016/j.jare... PMid:32257431 PMCid:PMC7113610.
Chilamakuri R, Agarwal S. COVID-19: Characteristics and therapeutics. Cells. 2021;10(2):206. https://doi.org/10.3390/cells1... PMid:33494237 PMCid:PMC7909801.
El-Zoghby SM, Soltan EM, Salama HM. Impact of the COVID-19 pandemic on mental health and social support among adult Egyptians. J Community Health. 2020;45(4):689-95. https://doi.org/10.1007/s10900... PMid:32468155 PMCid:PMC7255077.
Ornell F, Moura HF, Scherer JN, Pechansky F, Kessler FHP, von Diemen L. The COVID-19 pandemic and its impact on substance use: Implications for prevention and treatment. Psychiatry Res. 2020;289:113096. https://doi.org/10.1016/j.psyc... PMid:32405115 PMCid:PMC7219362.
Mousoulidou M, Siakalli M, Christodoulou A, Argyrides M. The impact of the COVID-19 pandemic on mental health: Evidence from Cyprus. Int J Environ Res Public Health. 2021;18(8):3868. https://doi.org/10.3390/ijerph... PMid:33917065 PMCid:PMC8067725.
Al-Jomaa EE, Al Meslamani A, Abazid H. A comparative cross-sectional study-knowledge, behavior and psychological change among medical and non-medical students in Jordan during COVID-19 pandemic. Jordan J Pharm Sci. 2022;15(2):204-13. https://doi.org/10.35516/jjps.....
Abazid H, Basheti IA, Al-Jomaa EE, Abazid A, Kloub WM. Public knowledge, beliefs, psychological responses, and behavioural changes during the outbreak of COVID-19 in the Middle East. Pharm Pract (Granada). 2021;19(2):2306. https://doi.org/10.18549/Pharm... PMid:34221198 PMCid:PMC8216710.
Henretty K, Padwa H, Treiman K, Gilbert M, Mark TL. Impact of the coronavirus pandemic on substance use disorder treatment: Findings from a survey of specialty providers in California. Subst Abuse. 2021;15:11782218211028655. https://doi.org/10.1177/117822... PMid:34285496 PMCid:PMC8264730.
Giuntella O, Hyde K, Saccardo S, Sadoff S. Lifestyle and mental health disruptions during COVID-19. Proc Natl Acad Sci USA. 2021;118(9):e2016632118. https://doi.org/10.1073/pnas.2... PMid:33571107 PMCid:PMC7936339.
Torales J, O’Higgins M, Castaldelli-Maia JM, Ventriglio A. The outbreak of COVID-19 coronavirus and its impact on global mental health. Int J Soc Psychiatry. 2020;66(4):317-20. https://doi.org/10.1177/002076... PMid:32233719.
Cénat JM, Blais-Rochette C, Kokou-Kpolou CK, et al. Prevalence of symptoms of depression, anxiety, insomnia, posttraumatic stress disorder, and psychological distress among populations affected by the COVID-19 pandemic: A systematic review and meta-analysis. Psychiatry Res. 2021;295:113599. https://doi.org/10.1016/j.psyc... PMid:33285346 PMCid:PMC7689353.
Holmes EA. O’Connor RC, Perry VH, et al. Multidisciplinary research priorities for the COVID-19 pandemic: A call for action for mental health science. Lancet Psychiatry. 2020;7(6):547-60. https://doi.org/10.1016/S2215-... PMid:32304649.
Liang L, Ren H, Cao R, et al. The effect of COVID-19 on youth mental health. Psychiatr Q. 2020;91(3):841-52. https://doi.org/10.1007/s11126... PMid:32319041 PMCid:PMC7173777.
Parola A, Rossi A, Tessitore F, Troisi G, Mannarini S. Mental health through the COVID-19 quarantine: A growth curve analysis on Italian young adults. Front Psychol. 2020; 11:567484. https://doi.org/10.3389/fpsyg.... PMid:33132973 PMCid:PMC7566042.
Stroud I, Gutman LM. Longitudinal changes in the mental health of UK young male and female adults during the COVID-19 pandemic. Psychiatry Res. 2021;303:114074. https://doi.org/10.1016/j.psyc... PMid:34271372 PMCid:PMC8520320.
Power E, Hughes S, Cotter D, Cannon M. Youth mental health in the time of COVID-19. Ir J Psychol Med. 2020;37(4): 301-5. https://doi.org/10.1017/ipm.20... PMid:32611470 PMCid:PMC7520633.
Gao J, Zheng P, Jia Y, et al. Mental health problems and social media exposure during COVID-19 outbreak. Plos One. 2020;15(4):e0231924. https://doi.org/10.1371/journa... PMid:32298385 PMCid:PMC7162477.
Li Y, Gu S, Wang Z, et al. Relationship between stressful life events and sleep quality: Rumination as a mediator and resilience as a moderator. Front Psychiatry. 2019;10:348. https://doi.org/10.3389/fpsyt.... PMid:31191370 PMCid:PMC6545794.
Dai L-L, Wang X, Jiang T-C, et al. Anxiety and depressive symptoms among COVID-19 patients in Jianghan Fangcang Shelter Hospital in Wuhan, China. Plos One. 2020;15(8): e0238416. https://doi.org/10.1371/journa... PMid:32857826 PMCid:PMC7454940.
Proops L, Grounds K, Smith AV, McComb K. Animals remember previous facial expressions that specific humans have exhibited. Curr Biol. 2018;28(9):1428-32. https://doi.org/10.1016/j.cub.... PMid:29706519.
Jemal K, Geleta TA, Deriba BS, Awol M. Anxiety and depression symptoms in older adults during coronavirus disease 2019 pandemic: A community-based cross-sectional study. SAGE Open Med. 2021;9:20503121211040050. https://doi.org/10.1177/205031... PMid:34434556 PMCid:PMC8381461.
Cook G, Burton L, Hoogenboom B. Pre-participation screening: The use of fundamental movements as an assessment of function–part 2. N Am J Sports Phys Ther. 2006;1(3):132-9.
Liu S, Yang L, Zhang C, et al. Gender differences in mental health problems of healthcare workers during the coronavirus disease 2019 outbreak. J Psychiatr Res. 2021;137:393-400. https://doi.org/10.1016/j.jpsy... PMid:33765451 PMCid:PMC7962932.
Magalhães M, Aparicio-García ME, García-Nieto I. Transition trajectories: Contexts, difficulties and consequences reported by young transgender and non-binary spaniards. Int J Environ Res Public Health. 2020;17(18):6859. https://doi.org/10.3390/ijerph... PMid:32961787 PMCid:PMC7558185.
Liu CH, Zhang E, Wong GTF, Hyun S, Hahm HC. Factors associated with depression, anxiety, and PTSD symptomatology during the COVID-19 pandemic: Clinical implications for US young adult mental health. Psychiatry Res. 2020;290:113172. https://doi.org/10.1016/j.psyc... PMid:32512357 PMCid:PMC7263263.
McLean CP, Asnaani A, Litz BT, Hofmann SG. Gender differences in anxiety disorders: Prevalence, course of illness, comorbidity and burden of illness. J Psychiatr Res. 2011;45(8):1027-35. https://doi.org/10.1016/j.jpsy... PMid:21439576 PMCid:PMC3135672.
Nolen-Hoeksema S, Jackson B. Mediators of the gender difference in rumination. Psychol Women Q. 2001;25(1):37-47. https://doi.org/10.1111/1471-6....